双类型鼻肉瘤:报告了两例用碳离子放射治疗治疗的病例
Kaoru Takahashi1, Masato Shino2, Kazuaki Chikamatsu1
1Department of Otolaryngology-Head and Neck Surgery, Gunma University Graduate School of Medicine.
Auris, nasus, larynx
|June 27, 2025
概括
双类型鼻肉瘤 (BSNS) 是一种罕见的双系瘤,在两名患者中使用碳离子放射治疗有效治疗. 这种创新方法对BSNS管理有很大的前景.
科学领域:
- 在瘤学瘤学.
- 辐射疗法 辐射疗法
- 病理学 病理学 病理学
背景情况:
- 双类型鼻肉瘤 (BSNS) 是一种罕见的恶性瘤,具有光滑肌肉和神经分化.
- BSNS诊断依赖于特征性免疫组织化学标记物和遗传分析.
研究的目的:
- 报告两例用碳离子放射治疗的双类型鼻肉瘤病例.
- 评估碳离子放射治疗对BSNS的治疗疗效.
主要方法:
- 详细的临床表现和诊断工作对两个BSNS患者.
- 免疫组织化学 (αSMA,S-100,SOX-10) 和基因分析 (PAX3融合) 用于瘤特征.
- 用碳离子放射治疗的治疗和结果的评估.
主要成果:
- 案例1:83岁的女性左鼻腔瘤,αSMA+,S-100+,SOX-10-,PAX3-MAML3融合阳性.
- 案例2:74岁男性右鼻前庭瘤,αSMA+,S-100+,SOX-10-,没有检测到PAX3融合.
- 两位患者在碳离子放射治疗后表现出有利的治疗效果.
结论:
- 碳离子放射疗法在治疗双类型鼻肉瘤方面表现出显著的疗效.
- 碳离子放射治疗代表了被诊断为BSNS的患者的潜在治疗策略.
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