对皮质神经假体视觉安全刺激参数进行端到端的学习
Burcu Küçükoğlu1, Bodo Rueckauer1, Jaap de Ruyter van Steveninck1
1Department of Machine Learning and Neural Computing, Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands.
Journal of neural engineering
|June 27, 2025
概括
这项研究引入了安全的大脑刺激恢复视力的新框架. 它优化了刺激参数,以更清晰地感知烯,同时确保视力受损者的生物安全.
科学领域:
- 神经科学是一个神经科学.
- 生物医学工程 生物医学工程
- 计算机科学 计算机科学
背景情况:
- 通过皮质视觉假肢直接电脑刺激提供了一条恢复视力障碍者的途径.
- 诱导 (感知光) 是关键的,但需要管理复杂的感官数据并确保安全的刺激水平.
研究的目的:
- 开发一个端到端的框架来学习最佳的大脑刺激参数 (振幅,脉冲宽度,频率).
- 为了确保刺激参数保持在安全的生物约束范围内.
- 为了提高烯视觉对假肢视力的解释性和有效性.
主要方法:
- 提出了一个端到端的学习框架来确定刺激参数.
- 集成了一个生物可信的烯模拟器,考虑到尺寸,亮度和时间动态.
- 使用自然主义导航视频验证了方法.
主要成果:
- 将刺激限制到安全水平维持了从素图像重建中的任务性能.
- 安全刺激参数导致了更有意义的色视觉.
- 该研究提供了对最佳刺激参数范围的见解.
结论:
- 开发的刺激生成编码器学习安全有效的刺激参数.
- 该框架通过使用现实的模拟器最大限度地实现图像重建和烯解释性.
- 这种方法强制执行视觉假肢的关键生物安全和硬件限制.
相关概念视频
Somatosensation
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
Sensory Functions of the Skin
The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
Overview of Somatic Sensory Pathways
Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
Visual System
Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...
Once through the pupil, the light passes through the lens, a...
Parallel Processing
The brain processes sensory information rapidly due to parallel processing, which involves sending data across multiple neural pathways at the same time. This method allows the brain to manage various sensory qualities, such as shapes, colors, movements, and locations, all concurrently. For instance, when observing a forest landscape, the brain simultaneously processes the movement of leaves, the shapes of trees, the depth between them, and the various shades of green. This enables a quick and...


