相关实验视频

Updated: May 4, 2026

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

Published on: June 13, 2014

酸功能化纳米材料用于向癌症治疗,诊断和治疗术

Abulfazl Vatankhah¹, Sepehr Hoseinzadeh Moghaddam², Fatemeh Oroojalian³

¹Natural Products and Medicinal Plants Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran; School of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran.

International journal of pharmaceutics

|June 27, 2025

概括

用酸 (SA) 修改的纳米材料通过与瘤细胞和免疫细胞结合来增强向癌症治疗. 这种方法改善了药物输送,提高了抗瘤疗效,并有助于癌症成像和治疗术.

科学领域:

生物医学工程生物医学工程
纳米技术纳米技术
癌症研究癌症研究

背景情况:

向性癌症治疗旨在提高疗效和减少副作用.
酸 (SA) 在许多瘤上过度表达,呈现出治疗点.
与免疫细胞的SA相互作用可以导致瘤免疫抑制.

研究的目的:

探索SA修饰纳米材料用于向癌症治疗的使用.
研究SA纳米材料在药物输送和免疫细胞调节方面的潜力.
为了评估SA-纳米材料在癌症成像和theranostics.

主要方法:

用酸 (SA) 修改纳米材料.
研究SA纳米材料与瘤细胞和表达Siglecs和selectins的免疫细胞的结合.
评估SA纳米材料的生物分布,细胞吸收和治疗疗效.
评估提供化学免疫治疗剂和成像剂的潜力.

主要成果:

经SA修饰的纳米材料表明瘤生物分布和细胞吸收的增强.
这些纳米材料有效向瘤细胞和瘤相关的免疫细胞,包括巨细胞.
SA-纳米材料促进治疗剂的传递,可能重编程免疫细胞并提高化疗的疗效.
当与SA纳米材料结合时,可增强成像和神经学剂的性能.

结论:

用酸修饰的纳米材料代表了针对癌症治疗的多功能平台.
这种方法提供了改进的药物输送,免疫调节和超神能力.
具有SA功能的纳米材料在推进精密瘤学方面具有重大前景.

关键词:

这是一种抗癌药物.癌症免疫疗法癌症免疫疗法癌症治疗术癌症治疗术诊断诊断诊断诊断诊断修改修改修改是一个酸是酸的一种.有针对性的癌症治疗.

更多相关视频

Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting

Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting

Published on: March 25, 2019

Biofunctionalization of Magnetic Nanomaterials

Biofunctionalization of Magnetic Nanomaterials

Published on: July 16, 2020

相关概念视频

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...

Microbial Corrosion

Microbial Corrosion

Microbiologically Influenced Corrosion (MIC) is a significant form of material degradation caused by the metabolic activities of microorganisms. This phenomenon poses substantial challenges across various industries, including oil and gas, maritime, and water treatment sectors.MIC occurs when microorganisms, such as bacteria, archaea, and fungi, colonize metal surfaces, forming biofilms that alter the local electrochemical environment. These biofilms can lead to the production of corrosive...