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可能的肉症对急性中风患者出院后不良结果的影响
Takafumi Abe1, Yoichi Sato1, Yosuke Kimura2
1Department of Rehabilitation, Uonuma Kikan Hospital, 4132 Urasa, Minami Uonuma-city, Niigata 949-7302, Japan; HEalth Promotional Physical Therapy for Stroke Survivors, Japan.
Clinical nutrition ESPEN
|June 27, 2025
概括
在住院的急性中风患者中可能出现的肉类与不良结果有关. 早期识别肉类可能有助于预测中风后患者的预后.
科学领域:
- 神经学 神经学
- 老年病的医生 老年病的医生
- 内部医学 内部医学
背景情况:
- 标志着肌肉质量和力量的损失的萨尔科佩尼亚,是老龄化人口日益关注的问题.
- 急性中风对健康构成重大挑战,复苏往往因伴随疾病而复杂化.
- 在入院时评估肌肉健康可能会为中风后的结果提供见解.
研究的目的:
- 调查急性中风患者入院时可能发生的肉类和不良事件之间的关联.
- 为了确定由小腿周长和手握强度定义的肉类,预测中风后的复发,再入院或死亡.
主要方法:
- 一项回顾性队列研究,涉及511名急性中风患者,在症状出现后48小时内入院.
- 使用2019年AWGS标准诊断了可能的肉症,评估了小牛周长和手握强度.
- 考克斯的比例危险回归分析被用来评估肉症和不良事件之间的关联,经过对混因子进行调整后.
主要成果:
- 在44.8%的研究队列中,确定了可能的肉类.
- 在调整后,可能的肉类与不良事件 (HR=3.94,p<0.001) 有显著的关联.
- 低的小腿周长和低的手握强度本身并没有与不良事件有显著的关联.
结论:
- 在入院时可能出现的肉类是急性中风患者不良结果的重要预测因素.
- 在入院时查肉类可能有助于对中风患者的预后评估.
- 进一步的研究可能会探索干预措施,以减轻中风幸存者中 Sarcopenia 相关的风险.
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