在回声心脏成像中,在患者中使用PYP和CMR的利用率和决定因素,这些患者患有无法解释的左心室缩
Nathaniel A Fessehaie1, Hilary Bediako2, Michael J Kallan3
1Department of Internal Medicine, Brigham and Women's Hospital, Boston, MA, United States of America.
International journal of cardiology
|June 27, 2025
概括
心脏粉症 (CA) 诊断率较低,只有8.2%的符合条件的患者接受进一步检测. 晚期疾病指标,如严重的腹功能障碍和壁壁厚度,增加了对CA的后续测试的可能性.
科学领域:
- 心脏病学 心脏病学
- 医学诊断 医学诊断 医学诊断
- 心脏成像 - - 心脏成像
背景情况:
- 心脏粉症 (CA) 是心力衰竭的未被确诊的原因,患病率和死亡率很高.
- 心声图是CA的关键查工具,但随后的诊断测试利用情况尚不清楚.
研究的目的:
- 调查心脏MRI (CMR) 和PYP扫描在患有暗示CA的心声图形特征的患者中的利用率.
- 确定与使用CMR和PYP扫描用于CA诊断相关的临床和心声学因素.
主要方法:
- 从2018年12月到2020年9月,对患者 (年龄≥18岁) 进行了回顾性队列研究,这些患者患有中度至严重的左心室缩和透静功能障碍,并接受了心声回声检查.
- 使用后勤回归模型来确定与接受CMR或PYP扫描相关的因素.
主要成果:
- 只有8.2% (83/1015) 的符合条件的患者接受了进一步的CA诊断测试.
- 与增加测试相关的因素包括年龄较大 (65岁以上),黑人种族,HFrEF诊断,严重的扩张功能障碍,严重的左心室壁厚度和心脏病学家订购的心声图.
结论:
- 对CA的后续诊断测试即使在具有暗示性心声学发现的患者中仍然很低.
- 表明疾病更晚期的特征与更高的进一步检测率有关,突出显示了早期诊断策略的必要性.
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