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超细胞性抗炎微环境 抑制了急性单细胞白血病细胞中乙胺诱导的DNA损伤

Margarita I Kobyakova1, Kirill S Krasnov2,3, Olga V Krestinina2

  • 1Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia. kobyakovami@gmail.com.

Biochemistry. Biokhimiia
|June 27, 2025
PubMed
概括

急性单细胞白血病 (AML-M5) 对化疗的耐药性是一个重大挑战. 这项研究揭示,一种促炎性微环境减少了DNA损伤,增加了AML细胞对像etoposide这样的拓酶抑制剂的耐药性.

关键词:
造成的DNA损伤是DNA损伤.急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.干扰子干扰子干扰子促炎性激活的发生.电阻的阻力可以

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