尿酸与高密度脂蛋白胆固醇比率和腹腔大动脉化之间的关联:一个横截面研究
1Department of Gastroenterology, Guangyuan Central Hospital (Li), Guangyuan, China.
Journal of clinical lipidology
|June 27, 2025
概括
尿酸与高密度脂蛋白胆固醇 (UHR) 的比率与腹腔大动脉化 (AAC) 风险的增加有关. 这种关联在AAC分数和严重AAC的女性中是显著的.
科学领域:
- 心血管健康 心血管健康
- 生物标志物研究 生物标志物研究
- 流行病学 流行病学
背景情况:
- 尿酸与高密度脂蛋白胆固醇比率 (UHR) 和腹腔大动脉化 (AAC) 之间的关系需要进一步研究.
- 以前的研究还没有完全阐明UHR和AAC之间的联系.
研究的目的:
- 检查40岁以上成年人UHR和AAC之间的关联.
- 探索UHR在预测AAC和严重腹腔大动脉化 (SAAC) 的诊断能力.
主要方法:
- 2013-2014年国家健康和营养检查调查 (NHANES) 数据的横截面分析.
- 使用加权多重逻辑和线性回归模型来评估UHR-AAC关系.
- 进行了子组,相互作用和接收器运行特征 (ROC) 曲线分析.
主要成果:
- 记录-UHR的1个单位的增加与更高的AAC分数和AAC和SAAC的几率增加有关.
- AAC和SAAC的风险在较高的UHR时显著增加.
- UHR和AAC/SAAC之间的关联因性别而异,在女性中显著.
结论:
- 在UHR和腹腔大动脉化风险之间存在积极的关联.
- 在女性子组中,UHR和AAC分数/SAAC之间的联系特别显著.
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