综述:在反动物牲畜中提供微量营养素,发展规划和战略补充
J S Caton1, M S Crouse2, C R Dahlen1
1Department of Animal Sciences, and Center for Nutrition and Pregnancy, North Dakota State University, Fargo, ND 58108, USA.
Animal : an international journal of animal bioscience
|June 27, 2025
概括
怀孕期间母亲的营养影响后代的发育,这一过程被称为发育编程. 战略性微量营养素补充可以减轻负面影响,改善胎儿发育和长期健康结果.
科学领域:
- 生殖生物学 生殖生物学
- 发展生物学 发展生物学
- 营养科学 营养科学
背景情况:
- 发育编程将子宫中的压力与母亲的营养不良联系在一起,导致后代的长期变化.
- 在大型动物模型中,母亲营养不良会影响胎儿发育和产后结果.
- 微量营养素供应至关重要,补充会影响胎盘功能和胎儿营养素的可用性.
研究的目的:
- 探索发展规划的概念及其机制.
- 研究母亲营养对后代发育的影响.
- 评估战略微量营养素补充剂在减轻负面规划影响中的作用.
主要方法:
- 利用大型动物模型,特别是反动物,研究母亲的营养效应.
- 分析了对后代发育的影响,包括内脏组织,新陈代谢,生长和繁殖.
- 检查了基因表达,代谢模式和生化途径的变化.
主要成果:
- 孕产妇营养不良会显著改变后代的发育和生理模式.
- 战略性微量营养素补充显示,有可能减轻不良的发育规划影响.
- 表观遗传机制和单碳代谢与发育编程有关.
结论:
- 怀孕期间母亲的营养是通过发育编程决定后代健康的关键因素.
- 微量营养素补充提供了一个有希望的策略来抵消负面编程.
- 需要进一步研究机制,畜牧业生产,动物健康和宿主微生物群相互作用.
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