扩大99DOTS用于结核病治疗监督:一个中断的时间序列分析
R Crowder1, S Nakasendwa2, A Kityamuwesi2
1Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California San Francisco, San Francisco, USA;, Center for Tuberculosis, University of California San Francisco, San Francisco, USA.
概括
像99DOTS这样的数字坚持技术显示出高患者入学率,并且不会对结核病治疗成功产生负面影响. 确保公平获取对于成功实施至关重要.
科学领域:
- 公共卫生 公共卫生
- 数字健康数字健康
- 传染病管理 传染病管理
背景情况:
- 结核病 (TB) 治疗的数字坚持技术 (DAT) 正在全球范围内扩大.
- 关于像99DOTS这样的DAT的有效性和可访问性的证据有限.
- 本研究评估了99DOTS在乌干达的扩大规模,重点是覆盖范围和有效性.
研究的目的:
- 在乌干达扩展期间评估99DOTS数字粘附技术的覆盖范围和有效性.
- 评估加强99DOTS干预对结核病治疗成功率的影响.
- 分析99DOTS注册和治疗完成的趋势.
主要方法:
- 使用中断时间序列设计,分析了3,526名药物敏感肺结核患者成年人的数据.
- 在2019年8月至2021年6月期间,从乌干达的12个卫生机构收集了数据.
- 该研究比较了实施增强99DOTS干预措施9个月前和12个月后的结果,包括提供电话和任务转移.
主要成果:
- 干预后,99DOTS入学率高达87.2%,略有上升趋势.
- 治疗完成率保持相似,干预后为89.8%,而干预前为87.1%.
- 干预后没有观察到治疗成功水平或趋势的显著即时变化.
结论:
- 当99DOTS数字粘附技术在适当的支持下实施时,可以在不影响结核病治疗结果的情况下实现高患者吸收率.
- 这些发现表明,在资源有限的环境中,DATs可以有效地扩展.
- 优先考虑获得公平的机会对于成功和包容性地在结核病治疗计划中实施数字坚持技术至关重要.
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