优化手术和药物治疗慢性鼻炎与鼻的长期结果
Wendong Liu1,2, Min Yan3, Haoran Lin4
1Department of Otolaryngology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
The Laryngoscope
|June 28, 2025
概括
长期鼻多发性鼻炎 (CRSwNP) 的内镜鼻手术 (ESS) 可以带来良好的结果. 药物坚持是改善CRSwNP患者ESS后结果的关键.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 过敏和免疫学 过敏和免疫学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 长期鼻炎与鼻息肉 (CRSwNP) 经常与2型炎症和严重症状有关.
- 透镜鼻手术 (ESS) 是一种常见的治疗方法,但长期的结果和影响因素需要实践调查.
研究的目的:
- 为了评估CRSwNP患者在ESS后1-7年后的术后控制状态.
- 确定影响ESS在CRSwNP管理中的长期成功的现实世界因素.
主要方法:
- 研究了一组427名接受双边ESS的成年CRSwNP患者.
- 315名患者的随访数据包括症状评分,内镜检查结果,CT扫描和血中乙酸细胞计数.
- 顺序逻辑回归分析了根据EPOS 2020标准影响临床控制的因素.
主要成果:
- 超过一半 (54.6%) 的患者在手术后实现了受控的CRSwNP状态,其中30.2%的部分控制和15.2%的不受控制.
- 糟糕的结果与高血中乙氨基比率,严重的嗅觉功能障碍 (嗅觉VAS>9.5) 和高的隆德-麦凯CT分数 (>14.5) 相相关.
- 药物坚持是改善术后控制的显著积极预测指标.
结论:
- 即使在2型炎症的情况下,ESS也可以为CRSwNP带来有利的结果.
- 优化外科手术技术和确保一致的药物坚持对于最大限度地提高患者在ESS后的益处至关重要.
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