评估动脉样硬化心血管疾病和癌症之间的共同风险因素:联系有多重要?
Brett Deng1, Shubh Desai1, Leslie Ynalvez1
1Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
Expert review of cardiovascular therapy
|June 28, 2025
概括
动脉硬性心血管疾病 (ASCVD) 和癌症具有共同的风险因素和生物途径. 了解这些联系可以改善这两种主要疾病的预防和治疗.
科学领域:
- 心血管医学 心血管医学
- 在瘤学瘤学.
- 病理生理学 病理生理学
背景情况:
- 动脉样性心血管疾病 (ASCVD) 和癌症是全球主要的死亡原因.
- 传统上被认为是单独的,新出现的证据表明ASCVD和癌症之间存在共同的风险因素和病理生理学.
- 这种重叠表明了共同的生物基础,需要综合的临床和研究重点.
研究的目的:
- 审查可修改的风险因素和ASCVD和癌症共同的病理机制.
- 探索炎症和氧化应激等共享途径如何为这两种疾病做出贡献.
- 突出统一预防和治疗策略的机会.
主要方法:
- 对可修改的生活方式和ASCVD和癌症的病理风险因素的文献综述.
- 对包括慢性炎症,氧化应激和荷尔蒙失衡在内的融合机械路径的分析.
- 检查综合护理和个性化医疗的新兴方法.
主要成果:
- 确定了共同的风险因素:吸烟,饮食不良,身体不活动,环境毒素,高血压,高脂血症,肥胖,胰岛素耐药性和性激素失调.
- 突出了常见的机制性途径:慢性炎症,氧化应激和荷尔蒙失衡.
- 强调了基于共享机制的统一预防和治疗策略的潜力.
结论:
- 了解ASCVD和癌症的共同基础对于双重风险分层和管理至关重要.
- 综合护理模式,个性化医疗和多学科专业知识对于优化患者治疗结果至关重要.
- 通过多主题和向治疗来进一步研究共享机制将推动针对ASCVD和癌症的双重负担的创新干预措施.
关键词:
心血管疾病是什么心血管疾病动脉样硬化 动脉样硬化癌症 癌症 癌症 癌症 癌症这是一种炎症炎症炎症炎症.营养 营养 营养 营养氧化应激是一种氧化应激.有关风险因素的风险因素.瘤微环境是一个微环境.更多相关视频
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