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Viktoriia Mushynska¹, Stepan Tistechok², Ivan Roman²

¹Laboratory of Reproductive Biotechnology, Institute of Animal Biology, National Academy of Agrarian Sciences of Ukraine, Lviv, 79034, Ukraine.

Current microbiology

|June 28, 2025

概括

肠球菌 (Enterococcus sp.) 是一种菌. 从卡尔巴蒂亚奶酪中分离出来的SB12具有益生菌潜力,因为它能够产生抗微生物细菌素. 基因组分析证实了它的遗传学位置,并确定了有益的特征以及有限的抗生素耐药性基因.

科学领域:

微生物学微生物学
基因组学就是基因组学.
食品科学食品科学食品科学

背景情况:

益生菌越来越多地用于畜牧业,作为抗生素的替代品.
某些Enterococcus faecium菌株因其抗微生物特性和胃肠道存活率而被用于益生菌中.
众所周知,Enterococcus菌株产生细菌素,这些细菌素表现出抗菌作用.

研究的目的:

进行基因组分析和Enterococcus sp.的表征. SB12是从卡尔巴特地区的奶酪中分离出来的.
评估Enterococcus sp. 的益生菌潜力. 在SB12中,它是SB12.
识别与细菌素合成,抗生素耐药性和毒性因素相关的基因.

主要方法:

全基因组测序和Enterococcus sp.的分析在SB12中,它是SB12.
遗传学分析以确定菌株的进化关系.
通过基因组分析识别抗生素耐药性基因和毒性因子.

主要成果:

这是Enterococcus sp.的基因组. SB12由一个染色体和两个质粒 (总大小为2.69 Mb) 组成.
遗传学分析将SB12置于具有已知的益生菌潜力的Enterococcus菌株中.
该基因组含有细菌素合成基因 (素A,SE-K4,P,溶素A,L50) 并表现出对高温,盐度,酶和低pH的耐药性.

结论:

肠球菌 (Enterococcus sp.) 是一种菌. SB12显示出作为益生菌剂的使用潜力很大.
该菌株具有有益的特征,包括产生细菌素和对恶劣条件的耐药性.
虽然检测到一些抗生素耐药性和毒性基因,但它们不被认为是主要的临床问题.

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