单个气球肠镜在患有遗传性多重症综合征的患者中的实用性,性能和安全性
Giuseppe Losurdo1, Raffaella Rima2, Antonella Castiglione Minischetti3
1Section of Gastroenterology, Department of Precision and Regenerative Medicine and Jonian Area, University of Bari, Bari, Italy. giuseppelos@alice.it.
单个气球肠镜 (SBE) 检测在遗传性多样性综合征中的小肠,与视频囊内镜 (VCE) 相当一致. 在SBE期间的多角切除术对于较大的多瘤是有效和安全的.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 遗传学 遗传学 是一个
背景情况:
- 遗传性多综合征显著增加了小肠多发育的风险.
- 早期检测和管理这些息肉对于患者的治疗结果至关重要.
研究的目的:
- 评估单个气球肠镜 (SBE) 对遗传性多综合征患者小肠多的诊断效果.
- 将SBE的诊断产量与视频囊内镜 (VCE) 进行比较.
- 评估SBE期间对这些多重体的多重切除术的疗效和安全性.
主要方法:
- 对患有家族性腺多样性 (FAP),皮茨-杰格斯综合征 (PJS),考登综合征 (CS) 和青少年多样性综合征 (JPS) 的患者进行回顾性分析,接受SBE和VCE.
- 统计分析包括K Cohen一致性指数,灵敏度,特异性,正负预测值和赔率比.
主要成果:
- 在54%的手术中检测到小肠多,跨越了各种多综合征.
- SBE与VCE相当一致 (k=0.33),对于较大的息肉 (>1厘米) 则达成更好的协议.
- 在13个会议中成功进行了多角切除术,用于1厘米以上的息肉,并发症率低 (一个出血,两个腹痛病例).
结论:
- 小肠多在遗传多综合征中很常见.
- 在这些患者中,SBE为诊断和治疗干预 (多角切除术) 提供了有价值的工具.
- SBE显示了多角切除术的低并发症率,使其成为一个可行的治疗选择.
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