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Updated: Sep 17, 2025

Isolation and Characterization of the Immune Cells from Micro-dissected Mouse Choroid Plexuses
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综合免疫衰老揭示TREM2/TIM3髓状细胞驱动大脑免疫逃避

Berta Segura-Collar1, Lucia Mondejar-Ruescas1, Denisse Alcivar-López1

  • 1Instituto de Investigaciones Biomédicas I+12, (Imas12) Hospital 12 de Octubre, Madrid, Spain; Dpto Anatomía Patológica, Hospital 12 de Octubre, Madrid, Spain.

EBioMedicine
|June 28, 2025
PubMed
概括

衰老的大脑表现出血脑屏障 (BBB) 功能障碍,导致神经炎症和骨髓细胞失衡. 针对这些途径可能为中枢神经系统疾病 (如阿尔茨海默氏症和质瘤) 提供新的治疗方法.

关键词:
年龄化 衰老 衰老阿尔茨海默氏症的疾病是阿尔茨海默氏症.质母细胞瘤 (glioblastoma) 是一个免疫逃避是免疫逃避的一种方式.时间3 TIM3在TREM2中,我们可以使用TREM2.

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