在驴子 (Equusasinus) 的双腔膜性表皮性间皮瘤
Shauna A Hilton1, Gail Leeming2, Jonathan Ruiz3
1School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Sutton Bonington, Loughborough LE12 5RD, UK.
Journal of comparative pathology
|June 28, 2025
概括
这项研究报告了驴子中第一个双腔体上皮质性间皮瘤病例. 这种罕见的癌症,以特定的细胞标志物为特征,在33岁的雌性Equus asinus中死后被诊断出.
科学领域:
- 兽医病理学 兽医病理学
- 比较瘤学 的比较.
- 马类医学 马类医学
背景情况:
- 间皮瘤是一种罕见的瘤,影响了各种动物物种.
- 在兽医文献中,以前没有关于驴子 (Equus asinus) 中间皮瘤的报道.
研究的目的:
- 为了记录和表征首次报告的驴子双洞性表皮性质间皮瘤病例.
- 提供这种罕见的马类瘤的组织病理学和免疫组织化学细节.
主要方法:
- 对33岁的雌驴进行了尸检和粗略检查,该驴出现了临床疾病迹象.
- 组织病理学评估来自体的瘤组织.
- 使用维门和细胞克拉标记物的免疫组织化学分析.
主要成果:
- 驴子出现了减肥,嗜睡,厌食症,心动减速,腹,以及延迟毛细血管补充时间.
- 粗略检查显示,在多叶膜和腹膜表面有大量的血清流血和多焦点结节.
- 组织病理学和免疫组织化学证实了透性上皮层层间皮瘤,具有阳性维门丁和细胞克拉丁染色.
结论:
- 这一病例代表了在驴子中首次被记录的双腔表皮性质间皮瘤的实例.
- 这些发现扩大了受这种罕见瘤影响的已知物种,并为马类瘤学知识做出了贡献.
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