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Updated: Sep 17, 2025

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C293作为一种具有对HIV-1整合酶和逆转录酶双重活性的新型支架

Sharif Karim Sayyed1, Marzuqa Quraishi1, Satish Kumar Rajasekharan2

  • 1Amity Institute of Biotechnology, Amity University Maharashtra, Bhatan, Panvel, Navi Mumbai, Maharashtra 410206, India.

Computational biology and chemistry
|June 28, 2025
PubMed
概括

一种新型化合物,C293,显示出作为HIV-1整合酶和逆转录酶的双重抑制剂的前景. 这一发现提供了一种潜在的新策略,可以对抗HIV耐药性,并改善治疗结果.

关键词:
抗逆转录病毒治疗方法艾滋病毒-1整合酶分子对接是分子对接.逆转录酶的使用方法链转移 (ST) 活动和RT抑制.

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