失去牙,饮食质量和认知能力下降:一项为期15年的纵向研究
Lewis Winning1, Danielle Logan2, Claire T McEvoy2
1Dublin Dental University Hospital, Trinity College Dublin, Lincoln Place, Dublin 2 D02 F859, Ireland.
The journal of nutrition, health & aging..
|June 28, 2025
概括
老年男性的牙脱落与轻度认知障碍 (MCI) 和痴呆症的风险更高有关. 饮食质量不佳部分解释了这种联系,突出了口腔健康问题.
科学领域:
- 老年学是指老年学的学科.
- 神经科学是一个神经科学.
- 牙科医学 牙科医学
背景情况:
- 牙脱落是老年人常见的问题.
- 认知能力下降,包括轻度认知障碍 (MCI) 和痴呆症,构成了重大的公共卫生挑战.
- 口腔健康,饮食和认知功能之间的关系需要进一步研究.
研究的目的:
- 检查牙脱落与MCI和痴呆症发病率之间的关联.
- 探索饮食质量在牙损失与认知衰退之间关系中的调解作用.
主要方法:
- 一个前性队列研究628社区居住的老年男性 (基线年龄为58-71岁).
- 牙科检查和认知评估 (识别正常认知,MCI或痴呆症) 在15年的中位数随访期间进行.
- 使用食物频率问卷评估了饮食多样性得分 (DDS);进行了调解分析.
主要成果:
- 失去牙 (定义为剩余的天然牙<20) 与MCI/痴呆症的发病率增加有显著的相关性 (OR=2.06).
- 饮食多样性得分部分介导了牙脱落和认知衰退之间的关系,约占该效应的23%.
- 这些发现被调整为完全调整的模型中的潜在混因素.
结论:
- 牙损失是老年男性患MCI和痴呆症的重要危险因素.
- 饮食质量在将口腔健康与认知结果联系起来的途径中充当部分调解者.
- 保持口腔健康和良好的营养可能对保持老年人群的认知功能至关重要.
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