新的癌症治疗创新与金融毒性之间的关联
Sara Khor1,2, Josh J Carlson1, Anirban Basu1
1Comparative Health Outcomes, Policy & Economics (CHOICE) Institute, University of Washington, Seattle, Washington, USA.
新的癌症治疗改善了生存率,但增加了患者的财务毒性. 这项研究发现,虽然晚期非小细胞肺癌 (NSCLC) 的生存率上升,但幸存者中的重大不良财务事件也有所增加.
科学领域:
- 在瘤学瘤学.
- 卫生经济学 卫生经济学
- 癌症护理研究 癌症护理研究
背景情况:
- 癌症治疗方法的进步提高了患者的生存率.
- 新型癌症治疗的成本上升引发了对财务毒性的担忧.
- 本研究研究了晚期非小细胞肺癌 (NSCLC) 的生存和财务毒性权衡.
研究的目的:
- 研究在晚期NSCLC患者中随着时间的推移改善的生存率和财务毒性之间的关系.
- 评估癌症治疗创新对患者财务福祉的影响.
- 评估癌症幸存者中不良金融事件的趋势.
主要方法:
- 使用链接的SEER癌症注册表和信用记录 (2013-2017) 的回顾性队列研究.
- 包括晚期NSCLC,膀,子宫,头和肝癌.
- 通过重大不利财务事件 (AFEs) 评估金融毒性,并使用后勤回归分析生存趋势.
主要成果:
- 对于NSCLC患者来说,两年生存率从15.2%增加到19.2% (2013-2017).
- 经历了AFE的幸存者增加了1.9%pt,而没有AFE的幸存者增加了2.2%pt.
- 在缺乏新疗法的晚期癌症的对照组中没有观察到类似的趋势.
结论:
- 从癌症治疗创新中获得的生存收益与增加的财务困难有关.
- 医疗保健的进步必须考虑金融毒性,以促进整体人口健康.
- 需要采取保护措施,以减轻接受癌症治疗的患者的经济困难.
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