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Updated: Sep 17, 2025

Establishment of Zebrafish Patient-Derived Xenografts from Pancreatic Cancer for Chemosensitivity Testing
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在患有晚期固体瘤的患者中,对zavondemstat (TACH101),一流的KDM4抑制剂进行第一阶段研究

Apostolia M Tsimberidou1, Farshid Dayyani2, David Sommerhalder3

  • 1Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

The oncologist
|June 28, 2025
PubMed
概括

一种表观遗传抑制剂Zavondemstat在患有晚期癌症的患者中安全且耐受良好. 初步结果显示了令人鼓舞的临床益处,需要进一步调查这种新型癌症治疗方法.

关键词:
KDM4 KDM4 KDM4 KDM4 KDM4 KDM4 KDM4 KDM4 KDM4 KDM4 KDM4 KDM4我们的TACH101是什么?这是表观遗传学.基因组 lysine 脱甲基酶 脱甲基酶扎沃德姆表示.

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