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Updated: Sep 17, 2025

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies
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一个路线图,以提高可靠性和数据共享在交联质谱的交联质谱.

Juri Rappsilber1, James Bruce2, Colin Combe1

  • 1Technische Universität Berlin, Chair of Bioanalytics, Berlin, Germany; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK; Si-M/""Der Simulierte Mensch"", a Science Framework of Technische Universität Berlin and Charité - Universitätsmedizin Berlin, Berlin, Germany.

Molecular & cellular proteomics : MCP
|June 28, 2025
PubMed
概括

交联质谱 (MS) 提供了对蛋白质相互作用和结构的洞察力. 协调数据格式和错误控制对于在结构生物学中可靠地交联MS数据至关重要.

关键词:
交叉连接质谱学质谱学.数据分析数据分析数据分析分享数据的数据共享.这是一个存储库存储库.标准化 标准化 标准化

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Peptide Identification Using Tandem Mass Spectrometry01:33

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Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...
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