听觉视觉交叉连接在感知扭曲的言语:一个与口腔裂变患者和典型的听众之间的比较
Yun Bai1, Minyue Cao1, Shaowei Liu2
1Department of Oral and Maxillofacial Surgery, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China; State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases (Nanjing Medical University), Nanjing, China; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing, China.
Neuroscience
|June 28, 2025
概括
患有裂的患者在语音感知过程中表现出减少的视听整合. 这项功能性磁共振成像 (fMRI) 研究揭示了听觉和视觉大脑区域之间的连接受损,影响了语音处理.
科学领域:
- 神经科学是一个神经科学.
- 语音感知研究研究 语音感知研究
- 医疗成像医学成像
背景情况:
- 裂口可以影响语音清晰度和听觉处理.
- 视听整合对于理解扭曲语音至关重要.
- 裂口口腔语音感知缺陷的神经机制尚未完全理解.
研究的目的:
- 在口腔裂患者的语音感知过程中调查视听交叉连接.
- 为了比较口腔裂患者和典型听众之间的大脑连接模式.
- 探索有效连接在与裂相关的语音处理缺陷中的作用.
主要方法:
- 基于任务的功能磁共振成像 (fMRI) 随机块设计.
- 使用动态因果建模 (DCM) 分析听觉和视觉皮层之间的区域相互作用.
- 感知任务涉及典型的和裂相关的喉停止语音刺激.
主要成果:
- 患有口腔裂变的患者在光停止感知过程中,从左上环到左下环的有效连接显著减少 (p=0.035).
- 在右上旋和右下旋之间没有发现连接性的显著差异.
- 研究结果表明,在口腔裂口组中,视听整合存在潜在的缺陷.
结论:
- palatal 裂口患者可能有受损的视听整合,影响语音感知.
- 减少跨模式连接可能是裂口口腔语言处理困难的基础.
- 这项研究提供了关于口腔裂发言障碍的神经基础的见解.
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