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光学连贯断层扫描血管图的纵向变化,在急性初级角度闭合眼镜的手术前后进行血管图

Ke Yin¹, Haomin Chen¹, Yanxin Zhang¹

¹Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, No. 251 Fukang Road, Xiqing District, Tianjin, 300384, China.

Photodiagnosis and photodynamic therapy

|June 28, 2025

概括

急性主角关闭 (APAC) 手术影响视网膜微血管,表面血管密度的变化与神经纤维层厚度相关. 这些表面的变化是亚太地区患者更敏感的指标.

科学领域:

眼科医生眼科眼科
视网膜成像视网膜成像
微血管研究微血管研究

背景情况:

急性初级角关闭 (APAC) 涉及突然的眼内压力 (IOP) 升高.
亚太地区对眼睛微血管系统的影响及其长期影响需要进一步研究.

研究的目的:

为了研究APAC患者手术后视网膜微血管结构的变化.
为了将这些微血管变化与视网膜神经纤维层 (RNFL) 和质细胞内状层 (GCIPL) 厚度相关联.
为了检查急性内血压升高对眼睛微血管结构的影响.

主要方法:

对22只亚太地区的眼睛和22只健康的眼睛进行了回顾性纵向研究.
光学连贯断层扫描血管造影 (OCTA) 用于评估表面 (SVC) 和深层 (DVC) 血管复合体中的血管密度 (VD).
在手术前和手术后测量 (1周,1个月) 的VD,RNFL和GCIPL厚度.

主要成果:

在术后,视盘和斑点中的SVC血管密度 (VD) 在一个月内显著下降.
深血管综合体 (DVC) 磁盘VD在一个月后也显示出显著的变化.
SVC VD 变化与 RNFL 和 GCIPL 厚度变化显著相关.
与DVC磁盘VD相比,SVC磁盘VD显示出更高的诊断性能.

结论:

在亚太地区,急性内压升高对眼睛微血管有持久的影响.
在SVC VD中术后的改变是监测亚太地区患者的更敏感的指标.

关键词:

急性初级角度闭合的急性初级角度闭合深血管复合体深血管复合体光学连贯性断层扫描血管图谱.表面血管综合体表面血管综合体

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