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Updated: Sep 17, 2025

Molecular Modulation by Lentivirus-Delivered Specific shRNAs in Endoplasmic Reticulum Stressed Neurons
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治疗神经退行性疾病的新目标:PKM2-STAT3-hnRNPA1反循环

Ping Ye1, Zhen Li1, Hong Jiang2

  • 1School of Public Health, China Medical University, Shenyang, Liaoning 110122, China.

Pharmacological research
|June 28, 2025
PubMed
概括

在像阿尔茨海默氏症这样的神经退行性疾病中,一个涉及酸激酶M2 (PKM2),信号转换器和转录3激活器 (STAT3) 和异质核核核核蛋白蛋白A1 (hnRNPA1) 的反循环至关重要. 了解这个循环提供了潜在的治疗目标.

关键词:
炎症性 炎症性 炎症性神经退行性疾病的神经退行性疾病在PKM2-STAT3-hnRNPA1反循环中.

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