初级保健中喘初始药理治疗趋势 (2010-2021):使用PHARMO数据网络进行的一项基于人口的研究
Joana Antão1, Guilherme Rodrigues1, Qichen Deng2
1Lab3R - Respiratory Research and Rehabilitation Laboratory, School of Health Sciences (ESSUA) and Institute of Biomedicine (iBiMED), University of Aveiro, Aveiro, Portugal; Department of Medical Sciences, University of Aveiro, Aveiro, Portugal; Department of Research and Development, Ciro, Horn, the Netherlands; Department of Respiratory Medicine, Maastricht University Medical Centre, NUTRIM Institute for Nutrition and Translational Research in Metabolism, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, the Netherlands.
荷兰的全科医生 (GPs) 改变了喘的处方模式,最初使用短效β-激动剂 (SABA) 而无吸入性皮质类固醇 (ICS) 增加,然后减少. 许多患者仍然在没有ICS的情况下接受SABA,这表明需要改进喘管理策略.
科学领域:
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
- 一般的做法一般的做法
背景情况:
- 在初级保健中喘管理缺乏广泛的现实世界数据.
- 了解最初的药理疗法对于提高喘护理质量至关重要.
研究的目的:
- 分析2010年至2021年期间荷兰全科医生 (GPs) 处方的初始喘药物治疗趋势.
- 为了比较不同年龄组和性别的治疗趋势.
主要方法:
- 一项使用PHARMO数据网络的重复横截面研究.
- 根据第一个处方在喘诊断后90天内确定初始治疗方法.
- 劳动者加入点回归用于趋势分析,并根据年龄和性别比较结果.
主要成果:
- 短效β-激动剂 (SABA) 单疗增加到2018年,然后下降;吸入性皮质类固醇长效β-激动剂 (ICS-LABA) 的使用减少,然后显著增加.
- 仅吸入性皮质类固醇 (ICS) 的处方显示中度增加,随后下降.
- 没有接受喘处方的患者数量有所减少,但没有ICS的SABA仍然普遍存在,特别是在年轻人中.
结论:
- 初始喘治疗的转变与更新的指导方针保持一致,但仍然存在低于最佳的处方 (无ICS的SABA).
- 很大一部分喘患者没有从全科医生那里获得处方,这突出了护理缺口.
- 与年龄相关的喘药物处方差异需要进一步调查和量身定制的干预措施.
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