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Updated: Sep 17, 2025

Inducing and Characterizing Vesicular Steatosis in Differentiated HepaRG Cells
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一阶段随机双盲研究,研究一种针对HSD17B13的RNA干扰治疗方法,用于与代谢功能障碍相关的脂肪肝炎

Arun J Sanyal1, Jorg Taubel2, Prajakta Badri3

  • 1Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University, Richmond, VA, USA.

Journal of hepatology
|June 28, 2025
PubMed
概括

拉皮罗西兰是一种针对HSD17B13的新疗法,在I期研究中显示出良好的安全性. 它显著降低了HSD17B13肝脏mRNA在患有代谢功能障碍相关的脂肪肝炎 (MASH) 的患者.

关键词:
这就是HSD17B13的原因.在RNAi疗法中使用RNAi疗法.肝脏疾病 肝脏疾病与代谢功能障碍相关的脂肪肝炎.非酒精性脂肪性肝病是非酒精性脂肪性肝病.

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