对比增强超声波对肝脏二维剪切波弹性图像的影响:在对比施用前是否需要进行弹性图像?
Jiayao Huang1, Qingyu Wu1, Bowen Zhuang1
1Sun Yat-sen University First Affiliated Hospital, Department of Medical Ultrasonics, Guangzhou, Guangdong, China.
与对比度增强的超声波 (CEUS) 暂时降低了来自二维剪切波弹性学 (2D-SWE) 的肝硬度测量,可能误诊肝纤维化. 肝炎会影响这种效应.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 医疗成像医学成像
- 弹性图形学 弹性图形学 弹性图形学
背景情况:
- 肝纤维化评估对于患者管理至关重要.
- 二维切割波弹性学 (2D-SWE) 是一种评估肝硬度的非侵入性方法.
- 与对比度增强的超声波 (CEUS) 用于肝损伤的表征和 perfusion 评估.
研究的目的:
- 调查CEUS对肝脏2D-SWE测量的动态影响.
- 分析CEUS如何影响2D-SWE.使用肝纤维化的评估.
- 确定CEUS对2D-SWE所观察到的影响背后的病理和生物因素.
主要方法:
- 从2023年8月到2024年8月,预计将招募220名参与者 (111名具有组织病理学).
- 2D-SWE测量是在CEUS前,在CEUS期间 (5-6分钟),CEUS后早期 (8-10分钟) 和CEUS后晚期 (25-30分钟) 进行的.
- 统计分析包括ANOVA进行相位比较和多变量线性回归以确定影响因素.
主要成果:
- 与CEUS前相比,CEUS和CEUS后早期阶段的平均肝硬度 (Emean) 显著下降 (p < 0.001).
- 在CEUS后后期 (p = 0.078) 时,Emean恢复到基线水平.
- 观察到纤维化和肝硬化评估的短暂下降,肝脏炎症活动与Emean减少的幅度独立相关.
结论:
- CEUS导致2D-SWE值的短暂降低,可能导致肝纤维化的低估.
- 肝脏炎症活动是影响2D-SWE降低程度后CEUS的一个关键因素.
- 这些发现强调了在解释纤维化病阶段的2D-SWE结果时考虑CEUS时间和肝炎的重要性.
更多相关视频
06:20Contrast-Enhanced Subharmonic Aided Pressure Estimation SHAPE Using Ultrasound Imaging with a Focus on Identifying Portal Hypertension
Published on: December 5, 2020
05:56Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
Published on: August 29, 2025
相关概念视频
Ultrasound II: Endoscopic Ultrasound and FibroScan
Endoscopic Ultrasound (EUS):
Ultrasonography
During an ultrasonography procedure, a handheld device called...
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
Imaging Studies II: Ultrasonography
Imaging Studies for Cardiovascular System V: CT
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
