纳米增强生物载体:铁氧化物修饰的奇托和甲基酸盐珠,以提高发酵效率和在泡柱生物反应器中的可重复使用性
David Abutu1,2,3, B O Aderemi1, A O Ameh1,3
1Department of Chemical Engineering, Ahmadu Bello University, Zaria, Kaduna, Nigeria.
Biotechnology letters
|June 29, 2025
概括
铁氧化物纳米颗粒增强酸盐和酸盐珠子对Saccharomyces cerevisiae的固定,提高乙醇产量和发酵中的载体耐用性.
科学领域:
- 生物技术是生物技术.
- 材料科学 材料科学 材料科学
- 化学工程是化学工程的重要组成部分.
背景情况:
- 酸盐珠 (CB) 和酸盐珠 (CAB) 常用于在发酵过程中使Saccharomyces cerevisiae固定.
- 它们的局限性包括机械强度低和表面积有限,这降低了乙醇产量.
研究的目的:
- 提高CB和CAB的机械强度和表面积,以改善Saccharomyces cerevisiae的固定.
- 研究氧化铁 (Fe2O3) 纳米颗粒对载体性能和乙醇生产的影响.
主要方法:
- 将Fe2O3纳米颗粒纳入CB和CAB.
- 在泡柱生物反应器中使用改性珠子将Saccharomyces cerevisiae固定.
- 半批发发酵在35°C,0.01L/分钟的空气流速,pH值为4.0 15小时.
主要成果:
- 加入Fe2O3显著增加了珠子的破裂力和表面积.
- 在修改的珠子中观察到增强的细胞吸附能力.
- 乙醇产量从37%提高到45%,提高了载体稳定性和可重复使用性.
结论:
- Fe2O3纳米颗粒的结合是一种有前途的策略,可以改善固定载体的机械性能和表面积.
- 这种增强导致更高的细胞吸附,增加了乙醇产量,并改善了酵母不动化的载体耐用性.
- 经过修改的珠子为工业发酵过程提供了稳定高效的平台.
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