影响肠道营养支持老年患者生存的因素
Tuğba Önder1, Çağatay Çavuşoğlu1, Ebru Öztürk2
1Department of Internal Medicine-Geriatrics, Gazi University Faculty of Medicine, Ankara, Turkey.
Journal of evaluation in clinical practice
|June 29, 2025
概括
男性的性别,年龄较大,高的LDH,低的IADL得分和更短的肠道营养 (EN) 持续时间与老年患者的生存率较差有关. 这些因素表明接受EN支持的患者存在潜在风险.
科学领域:
- 老年病的医生 老年病的医生
- 临床营养学 临床营养学
- 老年学是指老年学的学科.
背景情况:
- 在接受肠道营养 (EN) 的老年患者中,了解影响生存的因素对于优化护理至关重要.
- 临床和实验室特征对EN患者结果的影响仍然不完全理解.
研究的目的:
- 为了研究临床特征,老年评估得分和接受EN支持的老年人生存率之间的关联.
- 确定该患者群体中不良生存结果的预测因素.
主要方法:
- 对339名老年患者的回顾性分析,这些患者在老年诊所接受EN支持.
- 评估临床数据,综合老年病评估得分 (MNA-SF,ADLs,IADL,MMTs,GDS-SF) 和EN持续时间.
- 使用考克斯的比例危险模型分析了生存结果.
主要成果:
- 男性性别,年龄较大 (≥75岁),乳酸脱酶 (LDH) 升高,日常生活仪器活动 (IADL) 分数较低,EN 持续时间较短与生存时间较差有关.
- 减少EN持续时间1个月增加了死亡风险.
- 与口服营养支持 (ONS) 相比,皮肤内镜胃口 (PEG) 食与较低的生存率 (1年:50%,3年:12%).与口服营养支持 (1年:78%,3年:55%).
结论:
- 男性性别,年龄较大,LDH升高,IADL功能受损和EN持续时间缩短是接受EN治疗的老年患者生存率低下的潜在指标.
- 这些发现强调了全面的老年病学评估和监测EN持续时间的重要性,以改善患者的治疗结果.
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