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开发一个芯片上的容器作为病毒感染模型和用病毒模拟器进行抗病毒药物查平台

Jinho Kwon1, Hyeono Nam1, Joonha Park1

  • 1Department of Mechanical Engineering, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea.

ACS biomaterials science & engineering
|June 29, 2025
PubMed
概括

一个新的器官芯片模型有效模拟病毒感染和炎症. 这个平台有助于选抗炎药物作为潜在的抗病毒疗法,提供高通量解决方案.

关键词:
这是一种BRD4抑制剂.这是一个VCAM-1系统.聚I:C诱导的炎症血管生成是一种血管形成的过程.一个芯片上的船只.病毒模仿病毒模仿

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The cultivation of environmental microorganisms has long been hindered by the inability to replicate complex native conditions in vitro. The isolation chip (iChip) addresses this limitation by facilitating the growth of previously uncultivable microorganisms through in situ incubation. Designed for high-throughput microbial cultivation, the iChip comprises hundreds of microchambers, each capable of housing a single microbial cell. These microchambers are loaded with a mixture of molten agar and...