预测框架,用于估计来自对第二代抗凝血剂类杀虫剂的生态相关暴露对猛禽的风险
Ciara M Sanchez-Paredes1, Malcolm D Burgess2, Michael Fryer3
1Department of Environment and Geography, University of York, York YO10 5DD, UK.
The Science of the total environment
|June 29, 2025
概括
第二代抗凝固 Rodenticides (SGARs) 对鱼,特别是 Brodifacoum 构成致命的风险. 在猛禽繁殖季节避免使用SGAR可以减轻二次中毒风险.
科学领域:
- 环境毒理学环境毒理学
- 野生动物生态生态学
- 化学品风险评估 化学品风险评估
背景情况:
- 猛禽种群由于化学污染物而面临下降,许多物种中发现了第二代抗凝固 Rodenticide (SGAR) 残留物.
- 通过饮食接触SGARs会导致猛禽的二次中毒,但对跨生命阶段和使用模式的风险的理解是有限的.
研究的目的:
- 开发和应用一个新的建模框架来评估非目标物种的SGAR风险,使用普通作为案例研究.
- 通过模拟基于动物消费和SGAR使用水平的各种暴露场景来完善风险评估.
主要方法:
- 开发了一个建模框架来模拟四种类杀虫剂的高/低动物消耗和高/低SGAR使用.
- 场景评估了不同生命阶段对普通鱼的风险,与已确定的致命和次致命效应值相比.
主要成果:
- 发现布罗迪法暴露超过了致命和次致命效应值.
- 成年繁殖动物和幼面临来自Difethialone和Bromadiolone/Difenacoum混合物的次致命风险.
- 在以前安全的场景中,二西具有累积风险,在一周内达到值.
结论:
- 越来越多的布罗迪法库姆和迪费提阿隆的使用增加了猛禽中毒的风险.
- 在猛禽繁殖季节避免使用SGAR对于减少二次中毒至关重要.
- 开发的框架为SGARs的生态风险评估提供了一个工具,以指导监管和使用.
相关概念视频
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
182
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
182
01:12Relative Risk
361
Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
361