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中国居民的SARS-CoV-2感染频率和抑郁症状:一个适度调解模型
Yuan You1, Duo Zhang2, Jin Yu3
1Social Genetic and Developmental Psychiatry Centre, King's College London, London, SE5 8AF, UK.
Journal of psychiatric research
|June 29, 2025
概括
一次严重急性呼吸综合征冠状病毒 (SARS-CoV-2) 感染可能会减少抑郁症状,但多次感染会增加症状. 感知到的压力调解了这种效应,受社会经济地位 (SES) 的影响.
科学领域:
- 公共卫生 公共卫生
- 心理健康 心理健康
- 流行病学 流行病学
背景情况:
- 冠状病毒疾病2019 (COVID-19) 与抑郁症状有关.
- 重新感染严重急性呼吸道综合征冠状病毒 (SARS-CoV-2) 对心理健康构成风险.
- 有限的研究存在于SARS-CoV-2感染频率对压力和抑郁症的影响.
研究的目的:
- 调查SARS-CoV-2感染频率,感知压力和抑郁症状之间的关联.
- 通过感知压力来确定社会经济地位 (SES) 是否缓和SARS-CoV-2感染频率和抑郁症状之间的关系.
主要方法:
- 在2023年6月至8月期间,对30053名中国居民 (19至107岁) 进行了横截面研究.
- 参与者报告了SARS-CoV-2感染的频率;感知到的压力和抑郁症状使用经过验证的天平进行了测量.
- 统计分析包括MANOVA,ANOVA和条件间接影响分析,SES通过自我报告进行评估.
主要成果:
- 一个SARS-CoV-2感染与没有感染相比,抑郁症状较少,由感知到的压力介导,并由更高的SES放大.
- 多次SARS-CoV-2感染与抑郁症状增加相关.
- 感知到的压力在感染频率和抑郁症状之间的关系中起着调解作用.
结论:
- 重复的SARS-CoV-2感染在后疫情时代显著影响心理健康.
- 具有重复感染史的个人有更高的心理压力和抑郁症状的风险.
- 针对性心理健康支持对于受到重复感染影响的高风险人群至关重要.
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