不同尺寸和功能的纳米塑料的汗液诱导聚合:对皮肤透风险的全球和身体区域变异性的影响
Kunlin Chen1, Yanshan Huang2, Yaqi Zeng1
1College of Natural Resources and Environment, Key Laboratory of Arable Land Conservation (South China), MOA, Guangdong Provincial Key Laboratory of Agricultural & Rural Pollution Abatement and Environmental Safety, South China Agricultural University, 483 Wushan Road, Guangzhou, Guangdong 510642, China.
Journal of hazardous materials
|June 29, 2025
概括
汗水会导致纳米塑料聚集,影响它们如何深入穿透皮肤. 不同的纳米塑料类型和汗水条件会改变聚合和进入皮肤的风险,观察到区域差异.
科学领域:
- 环境科学 环境科学
- 材料科学 材料科学 材料科学
- 毒理学 毒理学 毒理学
背景情况:
- 纳米塑料 (20-50纳米) 是越来越普遍的环境污染物.
- 皮肤暴露于纳米塑料是越来越令人担忧的,因为潜在的皮肤透.
- 了解汗水等生物流体中纳米塑料的行为对于风险评估至关重要.
研究的目的:
- 为了研究各种聚烯纳米塑料在汗水中的聚合动力学.
- 评估与汗水诱导的纳米塑料聚合相关的皮肤透风险.
- 评估汗液成分和环境因素对纳米塑料聚合和透的影响.
主要方法:
- 在汗水标准中研究了未经修改 (PS20,PS50),氨基修改 (APS50) 和碳素修改 (CPS50) 聚烯纳米塑料的聚合.
- 使用全球汗水数据和皮肤模型评估纳米塑料透率.
- 分析了汗水pH值,度和特定成分 (尿素,乳酸,L-histidine) 对聚合的影响.
主要成果:
- 有负电荷的纳米塑料在酸性汗水中聚集最快; 有正电荷的APS50在性汗水中聚集最快.
- 聚合率受到颗粒和汗水度的影响,APS50和CPS50在酸性汗水中显示出高的异质聚合.
- 皮肤透潜力排名CPS50 > APS50 > PS20 > PS50;聚合减少了角层的透,但没有毛囊/腺体的入口.
- 全球透概率和流量各不相同,欧洲,南美和大洋洲的风险更高.
- APS50显示出更高的临界扩散度,表明透潜力更大.
结论:
- 汗水诱导的聚合显著调节纳米塑料皮肤透风险.
- 纳米塑料聚合和随后的皮肤透因纳米塑料的特性,汗水特性和地理位置而异.
- 特定的纳米塑料 (APS50,CPS50) 具有更高的皮肤透风险,特别是在某些身体区域和全球区域.
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