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口腔膜状细胞癌的皮肤转移:一个病例报告

Ana Letícia Mores¹, Caio Augusto Lima de Araujo², Fabio de Freitas Busnardo²

¹Oral Diagnosis Department, Semiology and Oral Pathology Areas, Faculdade de Odontologia de Piracicaba da Universidade Estadual de Campinas (UNICAMP), Piracicaba, SP, Brazil.

|June 29, 2025

概括

来自头部和部状细胞癌 (HNSCC) 的皮肤转移 (CM) 是罕见的,但表明预后不佳. 通过活检进行早期诊断对于管理这些具有挑战性的皮肤病变至关重要.

科学领域:

在瘤学瘤学.
皮肤病学皮肤病学
病理学病理学病理学

背景情况:

头角状细胞癌 (HNSCC) 的远程转移通常会影响肺部,肝脏和骨.
来自HNSCC的皮肤转移 (CM) 是罕见的,发生在0.7%-2.4%的病例中.
CM呈现为结节或斑点,经常模仿其他皮肤疾病,并与预后不佳 (37个月的中位生存期) 相关.

研究的目的:

报告一个由晚期口腔状细胞癌引起的皮肤转移病例.
突出在HNSCC患者中CM的诊断和管理挑战.

主要方法:

一个临床案例是57岁的男性患有晚期口腔状细胞癌的病例.
在放射治疗期间,患者在右臂和背部区域发生了皮肤转移.
由于疾病进展,进行了皮肤病变的息性外科切除.

主要成果:

患者在右臂出现了4x4厘米的结节性,红血性病变,伴有相关的疼痛.
多个皮肤病变被手术切除.
患者在皮肤转移的诊断后存活了45天.

结论:

在HNSCC患者中诊断和管理CM是具有挑战性的.
建议对HNSCC患者的任何新的皮肤病变进行快速切口活检.
早期诊断促进了适当和及时的治疗策略.

关键词:

案例报告案例报告皮肤转移的转移.头部和部的新生瘤.在口腔喉关节.皮肤转移的转移.

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