相关实验视频
Updated: Sep 17, 2025
10:42
Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
Published on: December 31, 2017
17.3K
在使用不同化物度的牙膏后,学龄前儿童口腔微生物组的变化
Wenhao Zhang1, Qiu Yan Xie2, Sui Huang3
1Department of Stomatology, Shenzhen Baoan Women's and Children's Hospital, Shenzhen, PR China.
Journal of dentistry
|June 29, 2025
概括
标准的化物牙膏 (1000 ppm) 通过减少有害细菌和增加有益物种,对儿童的口腔微生物组产生积极影响. 这种口腔微生物组的调节可能有助于预防牙.
科学领域:
- 微生物组研究的研究.
- 儿科牙科 儿科牙科
- 牙损伤预防 牙损伤的预防
背景情况:
- 牙损与口腔微生物组不平衡有关.
- 化物牙膏很常见,但其在不同度下对微生物的影响尚不清楚.
- 幼儿园儿童口腔微生物对化物牙膏的反应需要调查.
研究的目的:
- 评估牙膏中不同化物度对学龄前儿童口腔微生物组的短期影响.
- 为了比较标准化物 (1000 ppm),低化物 (500 ppm) 和非化物牙膏的影响.
主要方法:
- 48名学龄前儿童使用了指定的牙膏4周.
- 牙斑样本是在基线,第一周和第四周收集的.
- 微生物群体通过16S rDNA测序分析多样性和组成变化.
主要成果:
- 没有观察到总体微生物多样性 (α多样性) 的显著变化.
- 在化和非化组之间发现了微生物组成 (β多样性) 的显著差异.
- 标准的化物 (1000 ppm) 牙膏增加了有益的细菌 (如Streptococcus parasanguinis),并减少了潜在的有害细菌 (如Haemophilus).
结论:
- 化物牙膏,特别是1000ppm,调节学龄前儿童的口腔微生物群.
- 这种调节涉及减少有害细菌和促进有益物种,可能有助于预防.
- 研究结果支持使用标准的化物牙膏,以在儿科牙科护理中保持更健康的口腔微生物平衡.
相关概念视频
01:26Assessment of the Mouth
425
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
425
01:15Teeth
717
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
717