相关实验视频
Updated: Jun 27, 2026

12:27
Measuring Peptide Translocation into Large Unilamellar Vesicles
Published on: January 27, 2012
13.9K
CPPsite3:一个实验验验证的细胞透的更新的大型存储库
Nisha Bajiya1, Sohana Najrin2, Pankaj Kumar1
1Department of Computational Biology, Indraprastha Institute of Information Technology, Okhla Phase 3, New Delhi 110020, India.
Drug discovery today
|June 29, 2025
概括
细胞透 (CPP) 对于细胞内药物输送至关重要. 本综述详细介绍了CPP的进展,包括CPPsite3数据库和临床应用,以帮助药物输送研究.
科学领域:
- 生物化学 生物化学
- 药理学 药理学是指药理学的学科.
- 生物信息学是一种生物信息学.
背景情况:
- 在过去的20年中,细胞透 (CPP) 对于将药物输送到细胞中至关重要.
- CPP研究的进步需要更新的资源来发现和应用.
研究的目的:
- 提供CPP研究进展的系统概述.
- 强调CPPsite3数据库作为CPP发现的关键资源.
- 探索CPP在药物输送中的当前临床应用.
主要方法:
- 对CPP研究,实验技术和计算资源进行系统审查.
- 详细分析CPPsite3数据库,包括其与以前版本 (CPPsite,CPPsite2) 相比的增长.
- 探索已记录的CPP的临床应用.
主要成果:
- 在CPPsite3数据库中包含6788条条目,代表4285个独特的CPP.
- CPPsite及其继承者在CPP设计和预测方法开发中发挥了重要作用.
- 目前有几种CPP正在临床使用,证明了治疗潜力.
结论:
- 对于药物输送领域来说,CPP的进步,特别是CPPsite3数据库,是至关重要的.
- 本综述是CPP药物递送研究人员的综合资源.
- 进一步开发和利用CPP对未来的治疗方法具有重大前景.
相关概念视频
Subcellular Fractionation
The homogenate obtained after cell lysis contains various membrane-bound organelles that can be further separated into pure fractions by subcellular fractionation. These isolates are used to study specific cellular components, analyze localized protein activity, and are even employed in diagnostics. Fractionation is typically achieved using centrifugation methods, the most common being density-gradient and differential centrifugation.
Differential Centrifugation
Differential centrifugation is...
Differential Centrifugation
Differential centrifugation is...
Maintenance of the ES Cell State
The cells of the blastocyst inner cell mass only remain pluripotent for a short time. This state of pluripotency and self-renewal can be maintained in embryonic stem (ES) cell culture by adding specific chemicals or growth factors to ensure the cells can continue dividing and later differentiate into different cell types. In some cases, the cells are grown on a feeder layer of differentiated cells, which provides the growth factors and extracellular matrix components necessary for stem cell...
Storage
A schema is a mental framework that helps individuals organize and interpret information. Schemata, formed from previous experiences, influence how we process new information: how we encode it, the inferences we make, and how we retrieve it. For instance, a schema for what a typical classroom looks like might include desks, a teacher's desk, a whiteboard, and students in such an environment. This expectation helps us quickly understand and navigate new classrooms without needing to analyze each...

