新生儿和婴儿的发作和动
1David Geffen School of Medicine at UCLA, Harbor- UCLA, 1000 West Carson Street, Box 468, Torrance, CA 90509, USA.
Advances in pediatrics
|June 29, 2025
概括
区分婴儿发作和非发作事件至关重要. 真正发作的关键指标包括生命体征变化和刻板印象的运动,如果存在危险因素,则需要进一步的医疗评估.
科学领域:
- 儿科神经学 儿科神经学
- 新生儿科学 新生儿科学
- 发育儿科 发育儿科
背景情况:
- 婴儿和幼儿可能会表现出类似于发作的运动,但它们是良性的.
- 区分这些非发作事件与真正的发作对于适当的管理至关重要.
研究的目的:
- 概述临床特征,有助于区分发作和婴儿和儿童的非发作运动.
- 确定需要进一步调查发作障碍的风险因素.
主要方法:
- 临床观察和分析运动特征.
- 对已确定的发作风险因素进行病史审查.
主要成果:
- 非的运动往往缺乏生命体征变化,并且没有刻板印象.
- 发作指标包括生命体征变化,刻板印象的运动,跨环境发生,头/眼参与,抵抗重新定位,缺乏刺激触发器.
- 风险因素包括围产期缺氧缺血性脑病变,早产,新生儿重症监护室停留,遗传疾病,发育迟缓和先前的发作.
结论:
- 某些临床特征强烈表明儿科患者群体中的发作超过非发作.
- 患有有关病史和危险因素的儿童需要进行彻底评估,可能包括脑电图和神经成像,以确认或排除发作障碍.
相关概念视频
Seizures: Classification
609
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
609
Epilepsy and Seizures: Overview
293
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
293
Restless Leg Syndrome and Night Terrors
259
Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
259
Antiepileptic Drugs: Sodium Channel Blockers
927
Antiepileptic drugs are specialized medications that prevent seizures in individuals diagnosed with epilepsy. These drugs primarily function by blocking the movement of sodium ions through channels in the neuronal membrane, inhibiting the repetitive firing of action potentials often associated with seizures.
Sodium channel blockers modulate ion channels, particularly voltage-gated sodium channels. They block only sodium ion movement.
Among the most commonly prescribed antiepileptic drugs are...
Sodium channel blockers modulate ion channels, particularly voltage-gated sodium channels. They block only sodium ion movement.
Among the most commonly prescribed antiepileptic drugs are...
927
Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein
459
Antiepileptic drugs, such as levetiracetam (Keppra) and brivaracetam (Briviact), have emerged as crucial tools in managing epilepsy. These medications exert their therapeutic effects by targeting the synaptic vesicle protein SV2A, a transmembrane glycoprotein primarily found in the brain.
SV2A is a transmembrane glycoprotein located predominantly in the brain, modulating the release of neurotransmitters for neuronal communication. Both levetiracetam and brivaracetam exhibit a high affinity for...
SV2A is a transmembrane glycoprotein located predominantly in the brain, modulating the release of neurotransmitters for neuronal communication. Both levetiracetam and brivaracetam exhibit a high affinity for...
459
Antiepileptic Drugs: Calcium Channel Blockers
648
Calcium channel blockers, a class of antiepileptic drugs, regulate the flow of calcium ions within neurons.
Calcium channel blockers exert their antiepileptic effects by targeting T-type calcium channels, which are integral to transmitting nerve signals in the central nervous system. These channels allow the passage of calcium ions, which are vital for neuronal communication. By inhibiting T-type calcium channels, calcium channel blockers effectively reduce the release of neurotransmitters and...
Calcium channel blockers exert their antiepileptic effects by targeting T-type calcium channels, which are integral to transmitting nerve signals in the central nervous system. These channels allow the passage of calcium ions, which are vital for neuronal communication. By inhibiting T-type calcium channels, calcium channel blockers effectively reduce the release of neurotransmitters and...
648


