在患有外周动脉疾病的患者中,结合监督运动,营养建议和治疗教育的短期计划的有效性:一项回顾性队列研究
A Guézais1, M Talbot1, D Lanéelle2
1Inserm CIC 1414, Clinical Investigation Center, Univ Rennes, 35033 Rennes, France; Vascular Medicine Unit, CHU Rennes, Rennes, France.
Vascular diseases (Paris, France)
|June 29, 2025
概括
一个结合监督运动,营养和教育的简短计划显著改善了周围动脉疾病 (PAD) 患者的步行距离. 基线缺血症严重程度预测有改善,这表明较短的联合干预措施对PAD管理有效.
科学领域:
- 血管医学 血管医学
- 运动生理学 运动生理学
- 心血管疾病管理管理
背景情况:
- 监督运动训练 (SET) 对于下肢外周动脉疾病 (PAD) 管理至关重要,通常持续超过3个月.
- 对于PAD患者来说,SET的最佳持续时间仍然是持续讨论和研究的主题.
- 短期干预可以为传统的长期计划提供替代或补充的方法.
研究的目的:
- 为了评估一个简短的,多式方案 (SET,营养,教育) 在PAD患者最大步行距离 (MWD) 的有效性.
- 评估该计划对戒烟,LDL-c水平和医疗治疗优化的影响.
- 在研究队列中确定MWD改善的预测因素.
主要方法:
- 回顾性,单中心研究设计.
- 在干预前后评估脚-手臂指数 (ABI),MWD,以及运动前后的皮肤过氧压力 (DROP TcPO2).
- 计划前后的吸烟状态,LDL-c水平和药物坚持的文件.
主要成果:
- 一个短时间的课程 (中位数为23.5天) 显著增加了MWD的56% (P<0.001).
- 在戒烟率,LDL-c水平和医疗治疗优化方面,有所改善.
- 基线DROP TcPO2是MWD改善的唯一显著预测因子 (P<0.05).
结论:
- 一个短期的联合干预计划有效地增强了PAD患者的MWD和心血管风险因素.
- 该计划的成功与基线缺血严重程度有关,突出了运动TcPO2在患者选择中的价值.
- 这些发现支持PAD管理的更短,更全面的方案的有效性.
更多相关视频
06:13Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health
Published on: December 1, 2023
1.3K
12:59Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
Published on: July 5, 2017
12.7K
相关概念视频
01:27Peripheral Artery Disease III: Interprofessional Care
33
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
33
01:26Peripheral Artery Disease IV: Nursing Management
47
The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
47
01:23Peripheral Artery Disease V: Postoperative Nursing Management
28
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
28
01:30Peripheral Artery Disease I: Introduction
35
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
35
01:21Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
38
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
38
01:26Atherosclerosis III: Management
41
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
41