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2000年至2017年间芬兰移民中前列腺癌发病率和死亡率 - - 基于登记的队列研究
Katja M Mustonen1, Maarit H Lamminmäki2, Tytti M Sarkeala3
1University of Helsinki, Faculty of Medicine; Finnish Cancer Registry, Helsinki, Finland. katja.mustonen@cancer.fi.
Acta oncologica (Stockholm, Sweden)
|June 30, 2025
概括
与芬兰本土出生的男性相比,芬兰的移民男性的前列腺癌风险较低. 然而,与前列腺癌发病率相比,非西方男性的死亡率相对较高.
科学领域:
- 流行病学 流行病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 前列腺癌是一个重大的全球健康问题,不成比例地影响着老龄化人口.
- 现有研究强调了全球移民人口中癌症负担的差异.
- 在专门针对移民前列腺癌的研究中存在着显著的差距.
研究的目的:
- 调查芬兰移民男性中前列腺癌的发病率和死亡率.
- 为了比较移民群体 (西方和非西方) 与芬兰出生的男性的前列腺癌风险.
- 探索影响前列腺癌风险的因素,如居住时间和移民时的年龄.
主要方法:
- 分析了居住在芬兰的男性移民 (1973-2017) 的个人数据和芬兰出生的男性的总数据.
- 一项研究人口包括162,844名非西方男性和56,127名西方移民男性.
- 多变量波桑回归模型用于分析2000-2017年间不同移民群体的前列腺癌病例和死亡.
主要成果:
- 与芬兰出生的男性相比,非西方男性的前列腺癌发病率降低了33.7% (RR 0.663) 和死亡率降低了19.7% (RR 0.803).
- 西方男性的发病风险降低了12.4% (RR 0.876),但死亡率降低的趋势并不显著 (RR 0.78).
- 长时间居住和年轻的移民年龄与更高的前列腺癌风险有关.
结论:
- 与芬兰出生的男性相比,西方和非西方移民男性的前列腺癌总体风险较低.
- 与前列腺癌发病率相比,非西方移民男性可能会出现不成比例的高死亡率.
- 需要进一步的研究,以了解非西方移民中前列腺癌死亡率的相关影响.
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