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Updated: Sep 17, 2025

Ex Vivo Release of Calcitonin Gene-Related Peptide from the Trigeminovascular System in Rodents
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素基因相关 (CGRP) -表达神经元在外侧侧侧区域调节疼痛诱导的睡眠障碍

Nicole Lynch1, Roberto De Luca1, Richard L Spinieli1

  • 1Department of Neurology, Division of Sleep Medicine, and Program in Neuroscience, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, 02215, USA.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|June 30, 2025
PubMed
概括

急性疼痛通过激活特定的大脑电路来显著扰乱睡眠. 阻断素基因相关 (CGRP) 神经元在副核缓解疼痛引起的睡眠损失,提供新的治疗点.

关键词:
剧烈的疼痛是急性疼痛.神经电路中的神经电路.视觉遗传学 视觉遗传学一个副手臂核核.失眠 - 失眠 - 失眠

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