主要乳腺炎引起的病原体对抗微生物耐药性的趋势:一项为期九年的研究
Amir Moradi1, Behnam Bidarian1, Fatemeh Mohammadian1
1Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.
Veterinary medicine and science
|June 30, 2025
概括
乳腺炎病原体如大肠杆菌的抗微生物耐药性很高,特别是对泰洛辛的耐药性. 较大的农场和季节性因素影响多药耐药性,需要针对性干预来有效缓解.
科学领域:
- 兽医微生物学 兽医微生物学
- 抗微生物耐药性研究研究
- 乳制品群体健康 乳制品群体健康
背景情况:
- 乳制品农场的乳腺炎主要是由大肠杆菌,金黄色葡萄球菌和Streptococcus agalactiae引起的.
- 抗菌素耐药性 (AMR) 是一个日益严重的全球问题,严重影响兽医,并导致乳制品行业的经济损失.
研究的目的:
- 从2016年到2024年,回顾评估伊朗主要乳腺炎病原体的抗菌素耐药性模式.
- 确定这些病原体中影响多药耐药性的趋势和因素.
主要方法:
- 分析了来自不同规模的奶牛场的5275个牛奶样本.
- 对960个病原体分离物进行的抗菌感应性测试.
- 在9年的时间内对抗性模式进行了回顾性检查.
主要成果:
- 在所有测试的病原体中,特别是在大肠杆菌 (大肠杆菌) (91.63%) 中,泰洛耐药性非常普遍.
- 大肠杆菌的MDR率最高 (45.86%),其次是黄金杆菌 (30.4%) 和黄金杆菌 (22.05%).
- 对特定抗生素观察到显著的耐药性时间趋势,农场规模,临床状况和季节被确定为MDR的预测因素.
结论:
- 确定了导致乳腺炎病原体中MDR的关键因素,强调了AMR的复杂性.
- 量身定制的策略,包括改善农场管理,季节性干预和明智的抗菌药物使用,对于缓解耐药性至关重要.
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