在便免疫化学测试阳性患者中,前恶性和恶性病变的频率和模式
C S Hyder1, M A Uddin, M T Jalal
1Dr Chowdhury Sazzad Hyder, Assistant Professor, Department of Surgery, Shaheed Suhrawardy Medical College, Sher-e-Bangla Nagar, Dhaka, Bangladesh;
Mymensingh medical journal : MMJ
|June 30, 2025
概括
便免疫化学测试 (FIT) 能够有效地识别患有隐性出血的患者的前恶性腺瘤和其他结肠病理. 这种具有成本效益的查工具支持早期检测结直肠癌前体.
科学领域:
- 胃肠病学 胃肠病学
- 结肠直肠手术 结肠直肠手术
- 在瘤学瘤学.
背景情况:
- 结肠直肠癌对全球健康构成重大挑战,腺瘤多体作为关键前体.
- 早期检测结肠病理,如多和,对于有效的管理和癌症预防至关重要.
- 虽然结肠镜是黄金标准,但为了更广泛的可访问性,需要更少的侵入性查方法.
研究的目的:
- 通过便免疫化学测试 (FIT) 检测阳性患者的前恶性和恶性病变的频率和模式.
- 评估FIT作为查工具的实用性,用于识别重要的结肠发现.
主要方法:
- 一项观察性横截面研究,涉及105名FIT阳性患者接受结肠镜检查.
- 数据收集发生在2019年7月至2020年6月期间,发生在孟加拉国的结直肠外科和私立医院.
- FIT测试是由ICDDR'B.进行的.
主要成果:
- 在105名FIT阳性患者中,58人 (55.2%) 患有息肉,脚的息肉是最常见的 (40.0%).
- 在13.3%的病例中发现了,在2.9%的病例中发现了恶性外观的瘤,在12.4%的病例中发现了.
- 在44.7%和4.8%的患者中分别发现了腺瘤多和恶性瘤,在10.4%的患者中发现了晚期腺瘤.
结论:
- 便免疫化学测试 (FIT) 有效检测腺瘤,包括先进的腺瘤和前体病变,以及其他隐性出血来源,如.
- 结直肠查 (FIT) 作为一种有价值,具有成本效益的支持工具,用于结直肠癌查,特别是在资源有限的环境中.
- 虽然结肠镜仍然是最终的诊断程序,但FIT增强了结肠病理的早期检测工作.
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