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Updated: Jun 17, 2026

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
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开发具有量身定制的MMAE释放动态的多价值FAP向的小分子药物合物

Matilde Bocci1, Lucrezia Principi2, Dario Neri3

  • 1Philochem AG, Zürich, Switzerland.

Molecular cancer therapeutics
|June 30, 2025
PubMed
概括

针对纤维细胞激活蛋白 (FAP) 的小分子-药物结合物 (SMDC) 进行了比较. 不同的FAP抑制剂强度在临床前癌症模型中没有显著改变治疗疗效.

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