迷幻的悖论:一个催眠假设
1Kinsey Institute, Indiana University and Department of Psychology, University of Virginia, USA.
Comprehensive psychoneuroendocrinology
|June 30, 2025
概括
本综述探讨了血压素 (VP) 和催产素 (OT) 如何影响迷幻效应. 这些神经可能在与迷幻药物使用相关的焦虑和压力反应中发挥关键作用.
科学领域:
- 神经科学是一个神经科学.
- 心理药理学 心理药理学
- 内分泌学 在内分泌学.
背景情况:
- 迷幻药物可以引起短暂的心理和生理影响,包括焦虑和恶心.
- 脑下垂体-垂体-上腺轴和神经,如血管压素 (VP) 和催产素 (OT),都与应激反应有关.
- 压力经历后经常观察到催产素 (OT) 释放,其作用由VP调节.
研究的目的:
- 审查假设VP和OT系统是心理干预行为和生理结果的核心.
- 探索VP和OT在急性迷幻副作用 (如焦虑和疾病反应) 中的潜在参与.
- 检查VP-OT系统在压力反应激化中的作用及其与迷幻药物的相互作用.
主要方法:
- 现有科学文献的叙述性审查.
- 检查神经系统 (VP-OT) 和迷幻药物的作用之间的相互作用.
- 通过VP-OT轴对自主和免疫系统对迷幻效应的贡献的分析.
主要成果:
- 该VP-OT系统,以及下丘脑-垂体-上腺轴,可能会调解心理诱导的急性焦虑和疾病.
- 压力较大的经历,包括使用迷幻药的经历,可以触发OT释放,其效果由VP调节.
- VP-OT系统,自主神经系统和免疫系统之间的相互作用有助于压力反应.
结论:
- 假设VP-OT系统在心理使用的急性和潜在的长期后果中起着重要作用.
- 了解VP-OT系统的参与,可以完善幻化作用的模型,并为治疗应用提供信息.
- 对VP-OT系统和迷幻药物应用的hormetic原则可能为情绪和身体障碍提供新的治疗策略.
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