患有阻塞性睡眠呼吸暂停症候群的患者甲状腺功能障碍的患病率和关联分析:一项跨部门研究
Pinyi Zhou1, Hongmei Li2, Jingman Qiu1
1Department of Sleep Medicine, The Affiliated Hospital of Kunming University of Science and Technology, The First People's Hospital of Yunnan Province, Kunming, 650500, People's Republic of China.
Nature and science of sleep
|June 30, 2025
概括
甲状腺功能低下症影响13.7%的阻塞性睡眠呼吸暂停-呼吸暂停综合征 (OSAHS) 患者. 甲状腺功能与OSAHS的严重程度,性别和年龄有关,影响氧和水平.
科学领域:
- 内分泌学 在内分泌学.
- 睡眠医学 睡眠医学
- 肺部病理学 肺部病理学
背景情况:
- 阻塞性睡眠呼吸暂停-呼吸暂停综合征 (OSAHS) 经常与甲状腺功能低下有关.
- 了解OSAHS患者甲状腺功能低下症的患病率和相关性对于全面的患者管理至关重要.
研究的目的:
- 为了确定被诊断为OSAHS的患者中甲状腺功能低下的患病率.
- 调查甲状腺功能参数与OSAHS严重程度之间的相关性.
主要方法:
- 包括一个由1693名新诊断为OSAHS的患者组成的队列.
- 对所有参与者进行了多睡眠和甲状腺功能测试 (TSH,FT4).
主要成果:
- 甲状腺功能低下症在13.7%的OSAHS患者中存在 (3.8%明显,9.9%亚临床).
- 在调整后,甲状腺刺激激素 (TSH) 和自由甲状腺素 (FT4) 水平与OSAHS严重程度,性别和年龄相关.
- 过度的甲状腺功能低下与较低的最低氧和度 (LSpO2) 有关.
结论:
- 相当一部分OSAHS患者表现出甲状腺功能低下症.
- 甲状腺功能状况与OSAHS严重程度有关,并受人口因素的影响.
- 这些发现凸显了甲状腺功能障碍查在OSAHS患者中的重要性.
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