作为甲状腺结节发展的设置中的预测价值的主要压力:一个前性研究
Ebrahim Mohammadi1, Neda Valizadeh1, Reza Hatami Novi1
1Department of Internal Medicine, School of Medicine, Urmia University of Medical Sciences, Imam Khomeini Hospital, Urmia, Iran.
Caspian journal of internal medicine
|June 30, 2025
概括
甲状腺结节 (TN) 在女性中更常见,并且与辐射暴露,甲状腺疾病史和异常压力等因素有关. 早期识别和管理这些风险因素可以帮助减少TN发病率.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 甲状腺结节 (TN) 代表甲状腺细胞异常生长,全球发病率不断增加.
- 了解人口和环境因素对于预测TN风险至关重要.
研究的目的:
- 评估与甲状腺结节发病率相关的人口和环境因素.
- 为了确定预后风险因素来预测患上甲状腺结节的可能性.
主要方法:
- 一项病例控制研究涉及103名确诊TN患者和101名对照患者.
- 从2021年2月到2022年8月,通过检查清单收集的数据.
- 用单变量和多变量物流分析来确定风险因素.
主要成果:
- 在女性中,TN的患病率显著更高 (90.3%).
- 确定的主要危险因素包括电离辐射暴露 (83.5%),家族甲状腺疾病病史 (58.3%) 和不寻常的压力 (68.9%).
- 甲状腺功能低下 (37.9%),甲状腺功能过高 (7.8%) 和影响甲状腺的药物 (10.7%) 也与TN有关.
结论:
- 不寻常的压力在甲状腺结节的发展中起着重要作用.
- 早期诊断和管理风险因素,如压力,通过改变生活方式和意识,可以帮助减少TN发病率.
- 对于易受影响的人群,建议对有甲状腺疾病家族病史的个体进行查.
相关概念视频
Psychoneuroimmunology: Diabetes and Cancer
67
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
67
Synthesis and Regulation of Thyroid Hormones
5.2K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
5.2K
The Thyroid Gland
4.4K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
4.4K
Functions of Thyroid Hormones
3.2K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
3.2K
Psychoneuroimmunology: Cardiovascular Disease
82
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
82
Introduction to Stress and Lifestyle
201
Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
201


