快速进展的眼光障碍:治疗升级的临床,结构和社会经济驱动因素
Lok Hin Lee1, Yangyiran Xie1, Chris Bradley2
1Vanderbilt School of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America.
medRxiv : the preprint server for health sciences
|June 30, 2025
概括
快速的青光眼进展增加了积极治疗的几率,但只有不到25%的患者接受了治疗. 社会经济脆弱性也会影响视野损失患者的治疗选择.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 公共卫生 公共卫生
背景情况:
- 玻璃眼是导致不可逆转失明的主要原因.
- 快速的视野 (VF) 进展需要及时有效的治疗.
- 了解影响治疗选择的因素对于优化患者治疗结果至关重要.
研究的目的:
- 为了确定与快速VF进展的绿眼病患者的治疗选择相关的临床和社会人口学因素.
- 在治疗决策中分析视野下降,眼内压力 (IOP),眼睛结构和社会经济地位之间的关系.
主要方法:
- 从1,812名成年玻璃眼患者中对2,782只眼睛进行了回顾性队列研究.
- 分析包括人口,临床 (VF,OCT,IOP) 和社会经济 (SVI) 变量.
- 后勤回归确定了与治疗强度相关的因素 (医疗,微创,侵略性).
主要成果:
- 快速进展的患者接受侵略性手术 (OR 3.83) 和任何手术 (OR 3.15) 的几率更高.
- 更差的平均偏差 (MD) 和更小的边缘面积预测了积极的程序;更高的IOP预测了任何程序.
- 较高的社会脆弱性指数 (SVI) 与最小侵入性手术的可能性降低相关.
结论:
- 尽管VF进展迅速,但积极的干预措施未得到充分利用.
- 基线IOP和结构性严重程度影响了治疗选择,而不是仅仅影响了VF进展.
- 社会经济因素,特别是SVI,影响了接受侵入性较小的手术,突出了护理方面的差异.
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