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Updated: Sep 17, 2025

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
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多基因风险评分的祖先校准改善了非洲裔美国成年人的风险分层和影响估计

Luciana B Vargas1, Mariah C Meyer1, Iain R Konigsberg1

  • 1Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

medRxiv : the preprint server for health sciences
|June 30, 2025
PubMed
概括

使用遗传血统校准多基因风险评分 (PRS) 提高了对非洲裔美国人2型糖尿病和身高预测的准确性. 这种方法通过考虑特定种群的遗传变异来提高风险评估.

关键词:
添加剂 混合物 添加剂祖先校准的校准方法遗传相似性 遗传相似性高度 高度 高度 高度多基因风险得分 (PRS)风险预测风险预测2 型糖尿病 2 型糖尿病

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