实践效应持续了二十年的认知测试:对纵向研究的含义
Jeremy A Elman1,2, Erik Buchholz1,2, Rouhui Chen3
1Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.
medRxiv : the preprint server for health sciences
|June 30, 2025
概括
重复认知测试的实践效应 (PE) 持续数十年. 在纵向研究中考虑PEs可以改善认知衰退和轻度认知障碍 (MCI) 的检测.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 老年学是一门学科.
背景情况:
- 重复的认知测试可以导致练习效应 (PE),人工膨胀得分.
- 经过多次长期评估,PEs的持续性尚未得到充分理解.
研究的目的:
- 调查PE在从中年到老年多次评估中的持久性.
- 确定PE对认知轨迹和轻度认知障碍 (MCI) 患病率的影响.
主要方法:
- 在越南时代双胞胎老龄化研究 (VETSA) 中,分析了1608名男性的数据.
- 神经心理评估包括30项测量,分为4个波段 (~6年间隔),最长可达20年.
- 使用年龄匹配的替代参与者来估计PE,并使用未调整的与PE调整的得分比较认知轨迹.
主要成果:
- 在30项随访测试中,在7-12项测试中观察到显著的PE,特别是在情节性记忆和视觉空间领域.
- 对PEs进行调整显示,认知衰退的检测得到了改善.
- 经过PE调整,MCI患病率上升了多达20%.
结论:
- 实践效应是多次评估和几十年来持续存在的现象.
- 考虑到PEs对于准确解释纵向衰老研究中的认知变化至关重要.
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