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Updated: Sep 17, 2025

Analysis of Protein Folding, Transport, and Degradation in Living Cells by Radioactive Pulse Chase
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Published on: February 12, 2019

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折叠校正器与CFTR中第一个二元化核酸结合域之间的热力学合

Guangyu Wang1,2

  • 1Department of Physiology and Membrane Biology, University of California School of Medicine, Davis, CA, USA.

Research square
|June 30, 2025
PubMed
概括

折叠校正剂可以通过保护关键域来恢复囊性纤维化中的蛋白质折叠,从而实现正常功能所必需的二分化. 这种机制可能有利于患有F508del和罕见突变的患者.

关键词:
异质性通路的异质性通路合作折叠公司数字生物学 数字生物学能源景观 能源景观化的值值.非共价热结构的结构.保护性的折叠方式蛋白质的稳定性 蛋白质的稳定性

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