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Updated: Sep 17, 2025

Induction of Murine Intestinal Inflammation by Adoptive Transfer of Effector CD4+CD45RBhigh T Cells into Immunodeficient Mice
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RAB4A 驱动 CD4+ T 细胞通过 CD38 依赖 NAD+ 的代谢信号

Joy S Park1,2, Daniel Krakko1, Jessica Nolan1

  • 1Departments of Medicine, State University of New York, Upstate Medical University, Norton College of Medicine, Syracuse, New York 13210.

Research square
|June 30, 2025
PubMed
概括

在T细胞中的Rab4A蛋白通过增加CD38,减少NAD+和减少IL-2来驱动狼的炎症. 这一途径为系统性红斑狼 (SLE) 提供了新的治疗点.

关键词:
CD38 CD38 CD38 CD38 CD38 CD38 CD38 CD38 CD38 CD38 CD38 CD38 CD38 CD38CD4+ T 细胞是 CD4+ T 细胞.在IL-2中,IL-2被认为是IL-2.它们是NAD+NAD+NAD.拉伯4A 是一个字.这是自身免疫力.内体体内体流量是指内体体内体的流量.在mTOROR中使用mTOR.代谢 代谢 代谢 代谢系统性红血性狼 (Systemic Lupus Erythematosus) 是一种全身性狼.

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